Tina Cascone, MD, PhD
Disclosures: Paid consultant-AstraZeneca-|Paid consultant-Bristol-Myers Squibb-|Consulting Fee-Merck and Company, Inc.-|Honoraria-Roche- - 06/21/2021


Dr. Tina Cascone is an assistant professor, physician-scientist in the Department of Thoracic/Head and Neck Medical Oncology at the University of Texas MD Anderson Cancer Center in Houston, TX. She received her degree in medicine (summa cum laude) from the University of Campania Luigi Vanvitelli in Naples, Italy. She earned her doctorate degree in Medical and Surgical Oncology and Clinical Immunology at the same university and completed her postdoctoral studies at MD Anderson Cancer Center where she studied the impact of antiangiogenic therapy on the tumor microenvironment. She completed her residency training in internal medicine at the Barnes-Jewish Hospital/Washington University School of Medicine in St. Louis, MO, and then returned at MD Anderson Cancer Center for her medical oncology fellowship. In 2017, Dr. Cascone became an instructor in the Advanced Scholar Program at MD Anderson Cancer Center, and in 2018, she joined the faculty as a tenure-track assistant professor in the Department of Thoracic/Head and Neck Medical Oncology in the same institution.


Dr. Cascone leads a basic and translational research laboratory that houses state-of-the-art equipment acquired through a University of Texas Rising Stars Award. In 2018, she was chosen as a member of the MD Anderson Physician-Scientist Program. Dr. Cascone’s research program is focused on identifying immune-mediated mechanisms of tumor response and resistance to immune checkpoint therapies. She uses information generated from preclinical models and patient-derived samples to develop treatment strategies that may improve the cure rates of patients with operable non-small cell lung cancer. Dr. Cascone is the principal investigator on investigator-initiated and global randomized clinical studies evaluating the role of perioperative immune-based therapies for lung cancer patients. She also leads a comprehensive immunogenomic translational effort to study the dynamic changes in immune cell phenotypes on therapy and to identify biomarkers of therapeutic benefit. She is a past recipient of an ASCO Young Investigator Award, ASCO Career Development Award, and an American Society of Clinical Investigation (ASCI) Young Physician Scientist Award. Dr. Cascone is a co-principal investigator on an MPI NIH/NCI R01 grant award and on a multi-institutional research effort that recently received a prestigious Mark Foundation Endeavor award.